Article: HLA Class II Antigens and Their Interactive Effect on Perinatal Mother-To-Child HIV-1 Transmission.
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Luo M; Embree J; Ramdahin S; Bielawny T; Laycock T; Tuff J; Haber D; Plummer M; Plummer FA
PLoS ONE, 2015
10.1371/journal.pone.0126068.t004
The effect of HLA class II concordance on perinatal HIV-1 transmission.
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|
HIV+ children (n = 92) |
HIV- children (n = 162) |
p value(corrected) |
odds ratio (95%CI) |
| children DRB concordant with mother |
29 (31.95%) |
21 (12.96%) |
0.00035(0.0014) |
3.09 (1.64-5.83) |
| |
(n = 96) |
(n = (169) |
|
|
| children DPA concordant with mother |
43 (44.8%) |
67 (39.6%) |
n.s |
1.24 (0.74-2.05) |
| |
(n = 95) |
(n = 159) |
|
|
| children DPB concordant with mother |
24 (25.3%) |
34 (21.4%) |
n.s |
1.24 (0.68-2.26) |
| |
(n = 80) |
(n = 160) |
|
|
| children DQB concordant with mother |
27(33.8%) |
57(35.6%) |
n.s |
0.92 (0.52-1.62) |
Inferred neuron-electrophysiology data values
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